Alternative Wnt Signaling Activates YAP/TAZ

The transcriptional co-activators YAP and TAZ are key regulators of organ size and tissue homeostasis, and their dysregulation contributes to human cancer. Here we discover YAP/TAZ as bona fide downstream effectors of the alternative Wnt signaling pathway. Wnt5a/b and Wnt3a induce YAP/TAZ activation...

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Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Park, Hyun Woo, Kim, Young Chul, Yu, Bo, Moroishi, Toshiro, Mo, Jung-Soon, Plouffe, Steven W., Meng, Zhipeng, Lin, Kimberly C., Yu, Fa-Xing, Alexander, Caroline M., Wang, Cunyu, Guan, Kun-Liang
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538707/
https://ncbi.nlm.nih.gov/pubmed/26276632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.07.013
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