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Sequence, structure, and cooperativity in folding of elementary protein structural motifs

Residue-level unfolding of two helix-turn-helix proteins—one naturally occurring and one de novo designed—is reconstructed from multiple sets of site-specific (13)C isotopically edited infrared (IR) and circular dichroism (CD) data using Ising-like statistical-mechanical models. Several model varian...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lai, Jason K., Kubelka, Ginka S., Kubelka, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538684/
https://ncbi.nlm.nih.gov/pubmed/26216963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506309112
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