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High-resolution x-ray crystal structures of the villin headpiece subdomain, an ultrafast folding protein

The 35-residue subdomain of the villin headpiece (HP35) is a small ultrafast folding protein that is being intensely studied by experiments, theory, and simulations. We have solved the x-ray structures of HP35 and its fastest folding mutant [K24 norleucine (nL)] to atomic resolution and compared the...

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Main Authors: Chiu, Thang K., Kubelka, Jan, Herbst-Irmer, Regine, Eaton, William A., Hofrichter, James, Davies, David R.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140446/
https://ncbi.nlm.nih.gov/pubmed/15894611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502495102
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