Sequence-independent recognition of the amyloid structural motif by GFP protein family

Cnidarian fluorescent protein (FP) derivatives such as GFP, mCherry, and mEOS2 have been widely used to monitor gene expression and protein localization through biological imaging because they are considered functionally inert. We demonstrate that FPs specifically bind amyloid fibrils formed from ma...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Xu, Sherry C. S., LoRicco, Josephine G., Bishop, Anthony C., James, Nathan A., Huynh, Welby H., McCallum, Scott A., Roan, Nadia R., Makhatadze, George I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486722/
https://ncbi.nlm.nih.gov/pubmed/32839332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001457117
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