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Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron)

INTRODUCTION: HFE p.C282Y homozygosity is the most common cause of hereditary haemochromatosis. There is currently insufficient evidence to assess whether non-specific symptoms or hepatic injury in homozygotes with moderately elevated iron defined as a serum ferritin (SF) of 300–1000 µg/L are relate...

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書誌詳細
出版年:BMJ Open
主要な著者: Ong, Sim Yee, Dolling, Lara, Dixon, Jeannette L, Nicoll, Amanda J, Gurrin, Lyle C, Wolthuizen, Michelle, Wood, Erica M, Anderson, Greg J, Ramm, Grant A, Allen, Katrina J, Olynyk, John K, Crawford, Darrell, Kava, Jennifer, Ramm, Louise E, Gow, Paul, Durrant, Simon, Powell, Lawrie W, Delatycki, Martin B
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538285/
https://ncbi.nlm.nih.gov/pubmed/26270952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-008938
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