HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: a genotype-stratified cohort study of hemochromatosis in Australian women

BACKGROUND AND AIM: Women who are homozygous for the p.C282Y mutation in the HFE gene are at much lower risk of iron overload-related disease than p.C282Y homozygous men, presumably due to the iron-depleting effects of menstruation and pregnancy. We used data from a population cohort study to model...

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Detalhes bibliográficos
Publicado no:J Gastroenterol Hepatol
Main Authors: Warne, Charles D., Zaloumis, Sophie G., Bertalli, Nadine A., Delatycki, Martin B., Nicoll, Amanda J., McLaren, Christine E., Hopper, John L., Giles, Graham G., Anderson, Greg J., Olynyk, John K., Powell, Lawrie W., Allen, Katrina J., Gurrin, Lyle C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365371/
https://ncbi.nlm.nih.gov/pubmed/27784128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jgh.13621
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