טוען...
Reporter Gene Silencing in Targeted Mouse Mutants Is Associated with Promoter CpG Island Methylation
Targeted mutations in mouse disrupt local chromatin structure and may lead to unanticipated local effects. We evaluated targeted gene promoter silencing in a group of six mutants carrying the tm1a Knockout Mouse Project allele containing both a LacZ reporter gene driven by the native promoter and a...
שמור ב:
| הוצא לאור ב: | PLoS One |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4537176/ https://ncbi.nlm.nih.gov/pubmed/26275310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134155 |
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