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Phenotypic differences in viral immune escape explained by linking within-host dynamics to host-population immunity

Viruses that do not cause life-long immunity persist by evolving rapidly in response to prevailing host immunity. The immune-escape mutants emerge frequently, displacing or co-circulating with native strains even though mutations conferring immune evasion are often detrimental to viral replication....

詳細記述

保存先:
書誌詳細
出版年:J Theor Biol
主要な著者: Pepin, K.M., Volkov, I., Banavar, J.R., Wilke, C.O., Grenfell, B.T.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537168/
https://ncbi.nlm.nih.gov/pubmed/20570681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2010.05.036
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