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Phenotypic differences in viral immune escape explained by linking within-host dynamics to host-population immunity
Viruses that do not cause life-long immunity persist by evolving rapidly in response to prevailing host immunity. The immune-escape mutants emerge frequently, displacing or co-circulating with native strains even though mutations conferring immune evasion are often detrimental to viral replication....
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Publicado no: | J Theor Biol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4537168/ https://ncbi.nlm.nih.gov/pubmed/20570681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2010.05.036 |
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