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Within-Host Stochastic Emergence Dynamics of Immune-Escape Mutants

Predicting the emergence of new pathogenic strains is a key goal of evolutionary epidemiology. However, the majority of existing studies have focussed on emergence at the population level, and not within a host. In particular, the coexistence of pre-existing and mutated strains triggers a heightened...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Hartfield, Matthew, Alizon, Samuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365036/
https://ncbi.nlm.nih.gov/pubmed/25785434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004149
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