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Synthesizing within-host and population-level selective pressures on viral populations: the impact of adaptive immunity on viral immune escape
The evolution of viruses to escape prevailing host immunity involves selection at multiple integrative scales, from within-host viral and immune kinetics to the host population level. In order to understand how viral immune escape occurs, we develop an analytical framework that links the dynamical n...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894884/ https://ncbi.nlm.nih.gov/pubmed/20335194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2009.0560 |
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