Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production

Ribavirin is used as a component of combination therapies for the treatment of chronic hepatitis C virus (HCV) infection together with pegylated interferon and/or direct-acting antiviral drugs. Its mechanism of action, however, is not clear. Direct antiviral activity and immunomodulatory functions h...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Wang, Yang, McGivern, David R, Cheng, Liang, Li, Guangming, Lemon, Stanley M, Niu, Junqi, Su, Lishan, Reszka-Blanco, Natalia J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537094/
https://ncbi.nlm.nih.gov/pubmed/26274905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135232
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