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Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production
Ribavirin is used as a component of combination therapies for the treatment of chronic hepatitis C virus (HCV) infection together with pegylated interferon and/or direct-acting antiviral drugs. Its mechanism of action, however, is not clear. Direct antiviral activity and immunomodulatory functions h...
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Publié dans: | PLoS One |
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Auteurs principaux: | , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Public Library of Science
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4537094/ https://ncbi.nlm.nih.gov/pubmed/26274905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135232 |
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