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Δ(9)-Tetrahydrocannabinold (THC) suppresses secretion of IFNα by plasmacytoid dendritic cells (pDC) from healthy and HIV-infected individuals

Plasmacytoid dendritic cells (pDC) play a crucial role in host anti-viral immune response through the secretion of type I interferon. Interferon alpha (IFNα), a type I IFN, is critical for mounting the initial response to viral pathogens. A consequence of Human Immunodeficiency Virus-1 (HIV) infecti...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: Henriquez, Joseph E., Rizzo, Michael D., Schultz, Matthias A., Crawford, Robert B., Gulick, Peter, Kaminski, Norbert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527743/
https://ncbi.nlm.nih.gov/pubmed/28692581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001449
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