By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice

Cancer cells exhibit an altered metabolic phenotype known as the aerobic glycolysis. The expression of HK2 changes the metabolic phenotype of cells to support cancerous growth. In the present study, we investigated the inhibitory effect of resveratrol on HK2 expression and hepatocellular carcinoma (...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Dai, Weiqi, Wang, Fan, Lu, Jie, Xia, Yujing, He, Lei, Chen, Kan, Li, Jingjing, Li, Sainan, Liu, Tong, Zheng, Yuanyuan, Wang, Jianrong, Lu, Wenxia, Zhou, Yuqing, Yin, Qin, Abudumijiti, Huerxidan, Chen, Rongxia, Zhang, Rong, Zhou, Li, Zhou, Zheng, Zhu, Rong, Yang, Jing, Wang, Chengfen, Zhang, Huawei, Zhou, Yingqun, Xu, Ling, Guo, Chuanyong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2015
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537043/
https://ncbi.nlm.nih.gov/pubmed/25938543
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia