Protective Effects of Astaxanthin on ConA-Induced Autoimmune Hepatitis by the JNK/p-JNK Pathway-Mediated Inhibition of Autophagy and Apoptosis

OBJECTIVE: Astaxanthin, a potent antioxidant, exhibits a wide range of biological activities, including antioxidant, atherosclerosis and antitumor activities. However, its effect on concanavalin A (ConA)-induced autoimmune hepatitis remains unclear. The aim of this study was to investigate the prote...

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Veröffentlicht in:PLoS One
Hauptverfasser: Li, Jingjing, Xia, Yujing, Liu, Tong, Wang, Junshan, Dai, Weiqi, Wang, Fan, Zheng, Yuanyuan, Chen, Kan, Li, Sainan, Abudumijiti, Huerxidan, Zhou, Zheng, Wang, Jianrong, Lu, Wenxia, Zhu, Rong, Yang, Jing, Zhang, Huawei, Yin, Qin, Wang, Chengfen, Zhou, Yuqing, Lu, Jie, Zhou, Yingqun, Guo, Chuanyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356569/
https://ncbi.nlm.nih.gov/pubmed/25761053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120440
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