MicroRNA networks regulated by all-trans retinoic acid and Lapatinib control the growth, survival and motility of breast cancer cells

SKBR3-cells, characterized by ERBB2/RARA co-amplification, represent a subgroup of HER2(+) breast-cancers sensitive to all-trans retinoic acid (ATRA) and Lapatinib. In this model, the two agents alone or in combination modulate the expression of 174 microRNAs (miRs). These miRs and predicted target-...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Fisher, James Neil, Terao, Mineko, Fratelli, Maddalena, Kurosaki, Mami, Paroni, Gabriela, Zanetti, Adriana, Gianni, Maurizio, Bolis, Marco, Lupi, Monica, Tsykin, Anna, Goodall, Gregory J., Garattini, Enrico
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537007/
https://ncbi.nlm.nih.gov/pubmed/25961594
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