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Getting the genome in shape: the formation of loops, domains and compartments

The hierarchical levels of genome architecture exert transcriptional control by tuning the accessibility and proximity of genes and regulatory elements. Here, we review current insights into the trans-acting factors that enable the genome to flexibly adopt different functionally relevant conformatio...

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Pubblicato in:Genome Biol
Autori principali: Bouwman, Britta AM, de Laat, Wouter
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536798/
https://ncbi.nlm.nih.gov/pubmed/26257189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0730-1
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