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Getting the genome in shape: the formation of loops, domains and compartments

The hierarchical levels of genome architecture exert transcriptional control by tuning the accessibility and proximity of genes and regulatory elements. Here, we review current insights into the trans-acting factors that enable the genome to flexibly adopt different functionally relevant conformatio...

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Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Bouwman, Britta AM, de Laat, Wouter
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536798/
https://ncbi.nlm.nih.gov/pubmed/26257189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0730-1
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