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Getting the genome in shape: the formation of loops, domains and compartments

The hierarchical levels of genome architecture exert transcriptional control by tuning the accessibility and proximity of genes and regulatory elements. Here, we review current insights into the trans-acting factors that enable the genome to flexibly adopt different functionally relevant conformatio...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Bouwman, Britta AM, de Laat, Wouter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536798/
https://ncbi.nlm.nih.gov/pubmed/26257189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0730-1
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