The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma

Understanding the initiation and progression of pancreatic ductal adenocarcinoma (PDAC) may provide therapeutic strategies for this deadly disease. Recently, we and others made the surprising finding that PDAC and its preinvasive precursors, pancreatic intraepithelial neoplasia (PanIN), arise via re...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Krah, Nathan M, De La O, Jean-Paul, Swift, Galvin H, Hoang, Chinh Q, Willet, Spencer G, Chen Pan, Fong, Cash, Gabriela M, Bronner, Mary P, Wright, Christopher VE, MacDonald, Raymond J, Murtaugh, L Charles
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2015
Témata:
Developmental Biology and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536747/
https://ncbi.nlm.nih.gov/pubmed/26151762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07125
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