The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma

Understanding the initiation and progression of pancreatic ductal adenocarcinoma (PDAC) may provide therapeutic strategies for this deadly disease. Recently, we and others made the surprising finding that PDAC and its preinvasive precursors, pancreatic intraepithelial neoplasia (PanIN), arise via re...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Krah, Nathan M, De La O, Jean-Paul, Swift, Galvin H, Hoang, Chinh Q, Willet, Spencer G, Chen Pan, Fong, Cash, Gabriela M, Bronner, Mary P, Wright, Christopher VE, MacDonald, Raymond J, Murtaugh, L Charles
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Developmental Biology and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536747/
https://ncbi.nlm.nih.gov/pubmed/26151762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07125
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