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The group II metabotropic glutamate receptor agonist LY379268 reduces toluene-induced enhancement of brain-stimulation reward and behavioral disturbances
Toluene, a widely abused solvent with demonstrated addictive potential in humans, has been reported to negatively modulate N-methyl-D-aspartate receptors (NMDARs) and alter glutamatergic neurotransmission. The group II metabotropic glutamate receptor (mGluR) agonist LY379268 has been shown to regula...
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Pubblicato in: | Psychopharmacology (Berl) |
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Autori principali: | , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2015
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536139/ https://ncbi.nlm.nih.gov/pubmed/26044619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3973-3 |
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