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The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety
The activation of Group II metabotropic glutamate 2/3 (mGlu(2/3)) receptors reduces the excessive glutamate release that is hypothesized to be associated with neurodegenerative and psychiatric disorders. LY379268 is a highly potent mGlu(2/3) receptor agonist that has shown efficacy in several animal...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3765084/ https://ncbi.nlm.nih.gov/pubmed/23769742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2013.05.048 |
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