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The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety

The activation of Group II metabotropic glutamate 2/3 (mGlu(2/3)) receptors reduces the excessive glutamate release that is hypothesized to be associated with neurodegenerative and psychiatric disorders. LY379268 is a highly potent mGlu(2/3) receptor agonist that has shown efficacy in several animal...

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Bibliografiset tiedot
Päätekijät: Grivas, Vasilios, Markou, Athina, Pitsikas, Nikolaos
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765084/
https://ncbi.nlm.nih.gov/pubmed/23769742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2013.05.048
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