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The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety
The activation of Group II metabotropic glutamate 2/3 (mGlu(2/3)) receptors reduces the excessive glutamate release that is hypothesized to be associated with neurodegenerative and psychiatric disorders. LY379268 is a highly potent mGlu(2/3) receptor agonist that has shown efficacy in several animal...
Bewaard in:
| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3765084/ https://ncbi.nlm.nih.gov/pubmed/23769742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2013.05.048 |
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