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Chromothripsis and focal copy number alterations determine poor outcome in malignant melanoma
Genetic changes during tumorigenesis are usually acquired sequentially. However, a recent study showed that in 2 to 3% of all cancers a single catastrophic event, termed chromothripsis, can lead to massive genomic rearrangements confined to one or a few chromosomes. In order to explore whether the d...
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| 出版年: | Cancer Res |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4535704/ https://ncbi.nlm.nih.gov/pubmed/23271725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0928 |
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