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A New Whole Genome Amplification Method for Studying Clonal Evolution Patterns in Malignant Colorectal Polyps

To identify the genetic drivers of colorectal tumorigenesis, we applied array comparative genomic hybridization (aCGH) to 13 formalin-fixed paraffin-embedded (FFPE) samples of early, localized human colon adenocarcinomas arising in high-grade adenomas (so called “malignant polyps”). These lesions ar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hirsch, Daniela, Camps, Jordi, Varma, Sudhir, Kemmerling, Ralf, Stapleton, Mark, Ried, Thomas, Gaiser, Timo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535186/
https://ncbi.nlm.nih.gov/pubmed/22334367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.21937
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