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LGR5 positivity defines stem-like cells in colorectal cancer

Like normal colorectal epithelium, colorectal carcinomas (CRCs) are organized hierarchically and include populations of cells with stem-like properties. Leucine-rich-repeat-containing G-protein-coupled receptor 5 (LGR5) is associated with these stem cells in normal colorectal epithelium; however, th...

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Detalhes bibliográficos
Main Authors: Hirsch, Daniela, Barker, Nick, McNeil, Nicole, Hu, Yue, Camps, Jordi, McKinnon, Katherine, Clevers, Hans, Ried, Thomas, Gaiser, Timo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977143/
https://ncbi.nlm.nih.gov/pubmed/24282287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt377
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