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Statistical inference for extended or shortened phase II studies based on Simon’s two-stage designs

BACKGROUND: Simon’s two-stage designs are popular choices for conducting phase II clinical trials, especially in the oncology trials to reduce the number of patients placed on ineffective experimental therapies. Recently Koyama and Chen (2008) discussed how to conduct proper inference for such studi...

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書目詳細資料
發表在:BMC Med Res Methodol
Main Authors: Zhao, Junjun, Yu, Menggang, Feng, Xi-Ping
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535394/
https://ncbi.nlm.nih.gov/pubmed/26048655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-015-0039-5
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