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Proper inference from Simon’s two-stage designs
Simon’s two-stage designs are very popular for phase II clinical trials. A literature review revealed that the inference procedures used with Simon’s designs almost always ignore the actual sampling plan used. Reported P values, point estimates and confidence intervals for the response rate are not...
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| Publicado no: | Stat Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6047527/ https://ncbi.nlm.nih.gov/pubmed/17960777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3123 |
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