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Statistical inference for extended or shortened phase II studies based on Simon’s two-stage designs

BACKGROUND: Simon’s two-stage designs are popular choices for conducting phase II clinical trials, especially in the oncology trials to reduce the number of patients placed on ineffective experimental therapies. Recently Koyama and Chen (2008) discussed how to conduct proper inference for such studi...

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Detaylı Bibliyografya
Yayımlandı:BMC Med Res Methodol
Asıl Yazarlar: Zhao, Junjun, Yu, Menggang, Feng, Xi-Ping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535394/
https://ncbi.nlm.nih.gov/pubmed/26048655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-015-0039-5
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