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Statistical inference for extended or shortened phase II studies based on Simon’s two-stage designs
BACKGROUND: Simon’s two-stage designs are popular choices for conducting phase II clinical trials, especially in the oncology trials to reduce the number of patients placed on ineffective experimental therapies. Recently Koyama and Chen (2008) discussed how to conduct proper inference for such studi...
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| 出版年: | BMC Med Res Methodol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4535394/ https://ncbi.nlm.nih.gov/pubmed/26048655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-015-0039-5 |
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