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Ligand Migration in Human Indoleamine-2,3 Dioxygenase

Human indoleamine 2,3-dioxygenase (hIDO), a monomeric heme enzyme, catalyzes the oxidative degradation of L-tryptophan (L-Trp) and other indoleamine derivatives. Its activity follows typical Michaelis–Menten behavior only for L-Trp concentrations up to 50 µM; a further increase in the concentration...

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Bibliografske podrobnosti
izdano v:IUBMB Life
Main Authors: Nienhaus, Karin, Nickel, Elena, Lu, Changyuan, Yeh, Syun-Ru, Nienhaus, G. Ulrich
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535348/
https://ncbi.nlm.nih.gov/pubmed/21445845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.431
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