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Delivery of siRNA Silencing Runx2 Using a Multifunctional Polymer-Lipid Nanoparticle Inhibits Osteogenesis in a Cell Culture Model of Heterotopic Ossification

Heterotopic ossification (HO) associated with traumatic neurological or musculoskeletal injuries remains a major clinical challenge. One approach to understanding better and potentially treating this condition is to silence one or more genes believed to be responsible for osteogenesis by small inter...

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Publicado en:Integr Biol (Camb)
Autores principales: Mishra, Swati, Vaughn, Asa D., Devore, David I., Roth, Charles M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534437/
https://ncbi.nlm.nih.gov/pubmed/23146945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ib20200j
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