Synergistic Inhibition of Endochondral Bone Formation by Silencing Hif1α and Runx2 in Trauma-induced Heterotopic Ossification

Angiogenesis and osteogenesis are tightly coupled during bone development. We studied the effect of inhibition of Hif1α and Runt-related protein 2 (Runx2) on the formation of heterotopic ossification (HO). We constructed lentivirus vectors expressing Hif1α small interfering RNA (siRNA) and Runx2 siR...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lin, Lin, Shen, Qi, Leng, Huijie, Duan, Xiaoning, Fu, Xin, Yu, Changlong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2011
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149159/
https://ncbi.nlm.nih.gov/pubmed/21629226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.101
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