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Inhibition of connexin 43 prevents trauma-induced heterotopic ossification

Heterotopic ossification (HO) can result from traumatic injury, surgery or genetic diseases. Here, we demonstrate that overexpression of connexin 43 (Cx43) is critical for the development and recurrence of traumatic HO in patients. Inhibition of Cx43 by shRNA substantially suppressed the osteogenic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tu, Bing, Liu, Shen, Liu, Guangwang, Li, Zhiwei, Sun, Yangbai, Fan, Cunyi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111117/
https://ncbi.nlm.nih.gov/pubmed/27849058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37184
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