Loss-of-Function PTPRD Mutations Lead to Increased STAT3 Activation and Sensitivity to STAT3 Inhibition in Head and Neck Cancer

Lignende værker

• Genomic and Transcriptomic Alterations Associated with STAT3 Activation in Head and Neck Cancer
  af: Peyser, Noah D., et al.
  Udgivet: (2016)
• Frequent promoter hypermethylation of PTPRT increases STAT3 activation and sensitivity to STAT3 inhibition in head and neck cancer
  af: Peyser, Noah D., et al.
  Udgivet: (2015)
• Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis
  af: Ortiz, Berenice, et al.
  Udgivet: (2014)
• STAT3 as a chemoprevention target in carcinogen-induced head and neck squamous cell carcinoma
  af: Peyser, Noah D., et al.
  Udgivet: (2016)
• Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer
  af: Lui, Vivian Wai Yan, et al.
  Udgivet: (2014)