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Genomic and Transcriptomic Alterations Associated with STAT3 Activation in Head and Neck Cancer
BACKGROUND: Hyperactivation of STAT3 via constitutive phosphorylation of tyrosine 705 (Y705) is common in most human cancers, including head and neck squamous carcinoma (HNSCC). STAT3 is rarely mutated in cancer and the (epi)genetic alterations that lead to STAT3 activation are incompletely understo...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5113908/ https://ncbi.nlm.nih.gov/pubmed/27855189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166185 |
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