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The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions

Current strategies for early detection of breast and other cancers are limited in part because some lesions identified as potentially malignant do not develop into aggressive tumors. Acid pH has been suggested as a key characteristic of aggressive tumors that might distinguish aggressive lesions fro...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Tapmeier, Thomas T., Moshnikova, Anna, Beech, John, Allen, Danny, Kinchesh, Paul, Smart, Sean, Harris, Adrian, McIntyre, Alan, Engelman, Donald M., Andreev, Oleg A., Reshetnyak, Yana K., Muschel, Ruth J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534280/
https://ncbi.nlm.nih.gov/pubmed/26195776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509488112
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