Huntington’s disease: Neural dysfunction linked to inositol polyphosphate multikinase

Huntington’s disease (HD) is a progressive neurodegenerative disease caused by a glutamine repeat expansion in mutant huntingtin (mHtt). Despite the known genetic cause of HD, the pathophysiology of this disease remains to be elucidated. Inositol polyphosphate multikinase (IPMK) is an enzyme that di...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ahmed, Ishrat, Sbodio, Juan I., Harraz, Maged M., Tyagi, Richa, Grima, Jonathan C., Albacarys, Lauren K., Hubbi, Maimon E., Xu, Risheng, Kim, Seyun, Paul, Bindu D., Snyder, Solomon H.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534278/
https://ncbi.nlm.nih.gov/pubmed/26195796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511810112
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker