Inositol polyphosphate multikinase is a transcriptional coactivator required for immediate early gene induction

Profound induction of immediate early genes (IEGs) by neural activation is a critical determinant for plasticity in the brain, but intervening molecular signals are not well characterized. We demonstrate that inositol polyphosphate multikinase (IPMK) acts noncatalytically as a transcriptional coacti...

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Bibliographic Details
Main Authors: Xu, Risheng, Paul, Bindu D., Smith, Dani R., Tyagi, Richa, Rao, Feng, Khan, A. Basit, Blech, Daniel J., Vandiver, M. Scott, Harraz, Maged M., Guha, Prasun, Ahmed, Ishrat, Sen, Nilkantha, Gallagher, Michela, Snyder, Solomon H.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791727/
https://ncbi.nlm.nih.gov/pubmed/24043835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315551110
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