Inositol Polyphosphate Multikinase Is a Coactivator of p53-Mediated Transcription and Cell Death

The tumor suppressor protein p53 is a critical stress response transcription factor that induces the expression of genes leading to cell cycle arrest, apoptosis, and tumor suppression. We found that mammalian inositol polyphosphate multikinase (IPMK) stimulated p53-mediated transcription by binding...

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Bibliographic Details
Main Authors: Xu, Risheng, Sen, Nilkantha, Paul, Bindu D., Snowman, Adele M., Rao, Feng, Vandiver, M. Scott, Xu, Jing, Snyder, Solomon H.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108196/
https://ncbi.nlm.nih.gov/pubmed/23550211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003405
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