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Replacing SNAP-25b with SNAP-25a expression results in metabolic disease

Synaptosomal-associated protein of 25 kDa (SNAP-25) is a key molecule in the soluble N-ethylmaleimide–sensitive factor attachment protein (SNARE) complex mediating fast Ca(2+)-triggered release of hormones and neurotransmitters, and both splice variants, SNAP-25a and SNAP-25b, can participate in thi...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Valladolid-Acebes, Ismael, Daraio, Teresa, Brismar, Kerstin, Harkany, Tibor, Ögren, Sven Ove, Hökfelt, Tomas G. M., Bark, Christina
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534236/
https://ncbi.nlm.nih.gov/pubmed/26195742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511951112
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