SNAP-25 isoforms differentially regulate synaptic transmission and long-term synaptic plasticity at central synapses

SNAP-25 exists as two developmentally regulated alternatively spliced isoforms, SNAP-25a and SNAP-25b. We explored the function of SNAP-25a and SNAP-25b at Schaffer collateral-CA1 synapses in hippocampus using 4-week-old wild-type (WT) and SNAP-25b-deficient (MT) mice. Characterizing the protein exp...

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Publicat a:Sci Rep
Autors principals: Irfan, Muhammad, Gopaul, Katisha R., Miry, Omid, Hökfelt, Tomas, Stanton, Patric K., Bark, Christina
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484009/
https://ncbi.nlm.nih.gov/pubmed/31024034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42833-3
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