Silencing of survivin by YM155 induces apoptosis and growth arrest in hepatocellular carcinoma cells

Survivin overactivation is a frequent event in human hepatocellular carcinoma (HCC), due to its function in the induction of hepatocyte proliferation and apoptotic dysfunction. Recently, a novel survivin inhibitor named YM155, has demonstrated broad antitumor effects against various malignant tumors...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: ZHANG, CHANGHE, CAO, XIAOFEI, GEI, YONGXIANG, WANG, YONG, LIU, GUIYUAN, CHENG, GUOCHANG, LIU, QINGHONG
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2015
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533751/
https://ncbi.nlm.nih.gov/pubmed/26622722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3451
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