TAT-IL-24-KDEL-induced apoptosis is inhibited by survivin but restored by the small molecular survivin inhibitor, YM155, in cancer cells

Interleukin-24 (IL-24) is a cytokine belonging to the IL-10 gene family. This cytokine selectively induces apoptosis in cancer cells, without harming normal cells, through a mechanism involving endoplasmic reticulum (ER) stress response. TAT-IL-24-KDEL is a fusion protein that efficiently enters the...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Zhang, Jian, Xu, Rui, Tao, Xinyi, Dong, Yuguo, Lv, Xinxin, Sun, Aiyou, Wei, Dongzhi
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095056/
https://ncbi.nlm.nih.gov/pubmed/27203744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9458
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