Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells

BACKGROUND: Survivin, a member of the family of inhibitor of apoptosis proteins, functions as a key regulator of mitosis and programmed cell death. YM155, a novel molecular targeted agent, suppresses survivin, which is overexpressed in many tumor types. The aim of this study was to determine the ant...

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Bibliografiska uppgifter
Huvudupphovsmän: Tao, Yan-Fang, Lu, Jun, Du, Xiao-Juan, Sun, Li-Chao, Zhao, Xuan, Peng, Liang, Cao, Lan, Xiao, Pei-Fang, Pang, Li, Wu, Dong, Wang, Na, Feng, Xing, Li, Yan-Hong, Ni, Jian, Wang, Jian, Pan, Jian
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543843/
https://ncbi.nlm.nih.gov/pubmed/23267699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-619
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