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Lung Cancer Onset in Wild Type Mice Following Bone Marrow Reconstitution with kras(v12) Cells

A role for bone-marrow-derived cells (BMDCs) in tissue repair and malignancy onset has been proposed, but their contribution is still debated. We tested the ability of BMDCs containing the inducible kras(V12) oncogene to initiate lung adenocarcinoma. For our experimental strategy, we reconstituted l...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Belloni, Elena, Martin Padura, Ines, Gerbino, Elvira, Orecchioni, Stefania, Fusar Imperatore, Fulvia, Marighetti, Paola, Bertalot, Giovanni, Giuseppe Pelicci, Pier, Bertolini, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533313/
https://ncbi.nlm.nih.gov/pubmed/26267334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13047
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