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Lung Cancer Onset in Wild Type Mice Following Bone Marrow Reconstitution with kras(v12) Cells

A role for bone-marrow-derived cells (BMDCs) in tissue repair and malignancy onset has been proposed, but their contribution is still debated. We tested the ability of BMDCs containing the inducible kras(V12) oncogene to initiate lung adenocarcinoma. For our experimental strategy, we reconstituted l...

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Vydáno v:Sci Rep
Hlavní autoři: Belloni, Elena, Martin Padura, Ines, Gerbino, Elvira, Orecchioni, Stefania, Fusar Imperatore, Fulvia, Marighetti, Paola, Bertalot, Giovanni, Giuseppe Pelicci, Pier, Bertolini, Francesco
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533313/
https://ncbi.nlm.nih.gov/pubmed/26267334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13047
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