Lung Cancer Onset in Wild Type Mice Following Bone Marrow Reconstitution with kras(v12) Cells

A role for bone-marrow-derived cells (BMDCs) in tissue repair and malignancy onset has been proposed, but their contribution is still debated. We tested the ability of BMDCs containing the inducible kras(V12) oncogene to initiate lung adenocarcinoma. For our experimental strategy, we reconstituted l...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Belloni, Elena, Martin Padura, Ines, Gerbino, Elvira, Orecchioni, Stefania, Fusar Imperatore, Fulvia, Marighetti, Paola, Bertalot, Giovanni, Giuseppe Pelicci, Pier, Bertolini, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533313/
https://ncbi.nlm.nih.gov/pubmed/26267334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13047
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