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Lung Cancer Onset in Wild Type Mice Following Bone Marrow Reconstitution with kras(v12) Cells

A role for bone-marrow-derived cells (BMDCs) in tissue repair and malignancy onset has been proposed, but their contribution is still debated. We tested the ability of BMDCs containing the inducible kras(V12) oncogene to initiate lung adenocarcinoma. For our experimental strategy, we reconstituted l...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Belloni, Elena, Martin Padura, Ines, Gerbino, Elvira, Orecchioni, Stefania, Fusar Imperatore, Fulvia, Marighetti, Paola, Bertalot, Giovanni, Giuseppe Pelicci, Pier, Bertolini, Francesco
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533313/
https://ncbi.nlm.nih.gov/pubmed/26267334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13047
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