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TRPA1 mediates the hypothermic action of acetaminophen

Acetaminophen (APAP) is an effective antipyretic and one of the most commonly used analgesic drugs. Unlike antipyretic non-steroidal anti-inflammatory drugs, APAP elicits hypothermia in addition to its antipyretic effect. Here we have examined the mechanisms responsible for the hypothermic activity...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Gentry, Clive, Andersson, David A., Bevan, Stuart
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533162/
https://ncbi.nlm.nih.gov/pubmed/26227887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12771
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